Senior Director and Head, High Dimensional Biology & Drug Discovery Data Sciences
As head of the High Dimensional and Computational Biology team within Discovery Sciences, Pieter Peeters, Ph.D. leads a global team of data scientists and cell biology experimentalists focused on utilizing high dimensional biological and chemical data combined with artificial intelligence (AI)/machine learning (ML) algorithms to probe how a molecule impacts efficacy, safety & developability end-points – ultimately transforming our ability to invent the best NME, fastest. Based out of Beerse, Belgium, Pieter reports to Litao Zhang, Global Head, Discovery Technologies and Molecular Pharmacology in the Discovery Sciences organization and is a member of the DS Leadership Team. In addition to passion and enthusiasm, Pieter brings 20+ years of experience in the pharmaceutical industry to his leadership role. Most recently, he led the EU-based Computational Sciences (CS) team within Discovery Sciences. Under his leadership, the team led Janssen’s efforts in using AI and ML to translate high dimensional biological and chemical data to guide target discovery and mode of actions studies across all therapeutic areas. His team has successfully implemented several novel platforms such as the single cell immune profiling capability. In collaboration with partners across Jansssen R&D, the immune profiling platform has been successfully applied in unravelling the mode of action of DARZALEX® (daratumumab) as well as the discovery of T-cell receptors directed towards neo-antigens of relevance for treating prostate cancer. Pieter has been the Janssen lead for the ExaScience life lab, and the Innovative Medicine Initiative project on the application of induced pluripotent stem cells in drug discovery and drug safety testing (StemBANCC). In addition, Pieter was the recipient of the Philip B. Hofmann Research Scientist Award for leading work on liver-specific knockdown using SNALP-formulated siRNAs to study pathways in lipoprotein secretion and steatosis. He has authored or co-authored more than 40 peer-reviewed research publications and book chapters. Pieter was trained as a bio-engineer and obtained his Ph.D. in Applied Biological Sciences (medical molecular biology) at the Center for Human Genetics from the Catholic University Leuven, Belgium.